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Scott Briggs, an associate professor of biochemistry, and Paul South, a postdoctoral researcher, were looking at how histones, the proteins that DNA wraps itself around, are affected by environmental factors, a field called epigenetics. When histones are modified, they change how genes are expressed and how cells behave.One of the research team's yeast mutants lacks a methyltransferase called Set1, which is a protein that modifies histones. In this case, the lack of the methyltransferase decreases the amount of <a href=https://www.nike-dunks.de>nike store dunks ergosterol production. Ergosterol is the equivalent of human cholesterol, and the biological pathways that create ergosterol in yeast and cholesterol in humans are similar, with both being essential for cellular membrane formation and integrity."So, if we could actually design an inhibitor to this methyltransferase, we potentially could have another drug to lower cellular cholesterol converse plateau or one that new balance 480 could work in conjunction with current cholesterol-lowering drugs," said Briggs, who PESHAWAR:Inspector General of Police Nasir Khan Durrani approved the details of events fo stanley cup r Youm-e-Shuhada Police Day to be celebrated on August 14.The first organising committee meeting was held at Central Police Office on Sunday under the supervision of Additional IG Police Mian Muhammad Asif.According to the approved schedule, prayers will be held in all major mosques of the province and district police officers, along with other policemen, will also visit the graves of martyrs of on the morning of August 14 to pay tribute. Policemen will also visit the houses of officials who have lost their lives. Similarly, blood donation camps will also be arranged in various district headquarters hospitals on the regional level. At least 100 officers will donate their blood at these camps.Various speeches and compet new balance nere itions will also be held at all police training newbalance 574 schools and centres of Hangu. On this occasion, position holders will be awarded with cash prizes on the first day of the ceremony in P

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